• Cancer chemotherapeutic drug Cisplatin-induced acute emesis in monkeys

• Apomorphine-induced emetic responses in monkeys
• Emetic behavior quantified (time of occurrence and number of events)

-          Retching alone (a burst of rhythmic abdominal contractions without oral expulsion of upper gastrointestinal contents),

-          Vomiting alone (forceful oral expulsion of upper gastrointestinal contents)

-          Retching followed by a vomit.

-          The animals are then returned to their home cage and their condition monitored for a further 2 h and intermittently thereafter.

-          The presence of vomiting separated from the next bout by at least 1 min was considered as a single emetic episode